Key Takeaways from the Invokana Prescribing Information for Patients and Healthcare Providers

Key Takeaways from the Invokana Prescribing Information for Patients and Healthcare Providers

Invokana (canagliflozin) is an oral medication used to treat type 2 diabetes by helping the body remove excess glucose through urine. It is prescribed to patients whose blood sugar levels are not well controlled by diet and exercise alone. As with any medication, patients and healthcare providers should be aware of the benefits along with the risks associated with Invokana. This article will delve into the key takeaways from Invokana prescribing information for patients and healthcare providers.

How Does Invokana Work?

Invokana is classified as a sodiumglucose cotransporter 2 (SGLT2) inhibitor. It works by blocking the activity of SGLT2, a protein in the kidneys that reabsorbs glucose from the urine back into the bloodstream. By inhibiting SGLT2, Invokana reduces glucose reabsorption, causing more glucose to be excreted in the urine.

Invokana Dosage and Administration

The recommended dosage for Invokana is 100 mg once daily. It is usually taken in the morning with or without food. The dosage can be increased to 300 mg once daily in patients who require additional glycemic control. Invokana can be taken alone or in combination with other antidiabetic medications.

Invokana Side Effects

As with any medication, Invokana may cause side effects. Common side effects of Invokana include:

– Dehydration
– Genital yeast infections in women
– Urinary tract infections
– Increased urination
– Low blood sugar levels when used in combination with other antidiabetic medications

Some less common, but potentially serious side effects that require immediate medical attention include:

– Kidney problems
– Ketoacidosis (a serious condition in which the body produces high levels of blood acid)
– Lower limb amputation
– Fournier’s gangrene (a rare but severe bacterial infection that affects the genital or perineal area)

Invokana Precautions and Contraindications

Invokana is contraindicated in patients with a history of serious hypersensitivity reactions, severe renal impairment, or end-stage renal disease on dialysis. It should be used with caution in patients with a history of genital mycotic infections or urinary tract infections. Patients who experience dehydration, severe infection, acute illness, or who are undergoing surgery, may require temporary discontinuation of Invokana.

Invokana Interactions

Invokana may interact with other medications, including diuretics and insulin. Patients should inform their healthcare provider of all medications they are taking to avoid any potential interactions.

Conclusion

Invokana is a medication used to treat patients with type 2 diabetes. It works by blocking the activity of SGLT2, a protein in the kidneys that reabsorbs glucose from the urine back into the bloodstream. Invokana has common side effects that include dehydration, genital yeast infections, urinary tract infections, and low blood sugar levels when used in combination with other antidiabetic medications. It is contraindicated in patients with a history of serious hypersensitivity reactions, severe renal impairment, or end-stage renal disease on dialysis. Invokana may interact with other medications, and patients should inform their healthcare provider of all medications they are taking. By being aware of the benefits and risks associated with Invokana, patients and healthcare providers can manage type 2 diabetes effectively.

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